Frazier Life Sciences Management, L.P.
13F filer · CIK 1892134 · Palo Alto, CA
Summary
Frazier Life Sciences Management, L.P. reported $4.59B across 41 positions in its 13F for 2026 Q2, filed Aug 14, 2026. The largest holdings are MIRM (19.6%), NAMS (13.3%), ERAS (10.0%). Versus 2026 Q1, leaving options aside, it opened 6 new positions, added to 8, trimmed 2 and sold out of 3.
Reported value$4.59B
Positions41
Report period2026 Q2
FiledAug 14, 2026
New positions6
Added8
Trimmed2
Sold out3
Top 25 holdings
By reported value, options listed separately · change vs 2026 Q1
Weight 19.6%Value $899.06MPrice $87.54Shares 7.68MSince Jun 30 -25.22%
Weight 13.3%Value $613.03MPrice $23.81Shares 18.09M +6.76%Since Jun 30 -29.74%
Weight 10.0%Value $457.55MPrice $14.21Shares 24.98M +1.22%Since Jun 30 -22.43%
Weight 8.0%Value $367.19MPrice $57.75Shares 6.65MSince Jun 30 +4.62%
Weight 5.6%Value $258.91MPrice $26.75Shares 9.87MSince Jun 30 +2.02%
Weight 4.0%Value $185.37MPrice $14.42Shares 9.94M -0.00%Since Jun 30 -22.68%
Weight 3.9%Value $178.89MPrice $335.06Shares 481KSince Jun 30 -9.85%
Weight 3.3%Value $150.18MPrice $27.02Shares 5.03M +10.20%Since Jun 30 -9.45%
Weight 2.9%Value $135.26MPrice $7.36Shares 12.47MSince Jun 30 -32.17%
Weight 2.9%Value $134.85MPrice $139.00Shares 882KSince Jun 30 -9.04%
Weight 2.5%Value $115.31MPrice $65.97Shares 1.55M -55.10%Since Jun 30 -11.43%
Weight 2.2%Value $99.09MPrice $65.87Shares 1.35MSince Jun 30 -9.94%
Weight 2.2%Value $98.81MPrice $65.64Shares 1.16MSince Jun 30 -22.95%
Weight 1.5%Value $70.03MPrice $16.21Shares 3.15MSince Jun 30 -27.01%
Weight 1.3%Value $60.05MPrice $246.23Shares 225K +68.87%Since Jun 30 -7.68%
Weight 1.3%Value $59.88MPrice $5.08Shares 9.72MSince Jun 30 -17.53%
Weight 1.1%Value $52.57MPrice $31.91Shares 1.92MSince Jun 30 +16.59%
Weight 1.1%Value $50.41MPrice $6.15Shares 7.10M +39.22%Since Jun 30 -13.38%
Weight 1.1%Value $49.72MPrice $7.69Shares 7.61MSince Jun 30 +17.76%
Weight 1.0%Value $46.83MPrice $18.33Shares 2.54MSince Jun 30 -0.43%
Weight 1.0%Value $46.69MPrice $1.62Shares 22.45M +491.22%Since Jun 30 -22.12%
Weight 1.0%Value $45.86MPrice $76.69Shares 729KSince Jun 30 +21.85%
Weight 0.9%Value $40.09MPrice $8.27Shares 4.01MSince Jun 30 -17.30%
Weight 0.8%Value $36.71MPrice $40.80Shares 701KSince Jun 30 -22.13%
Weight 0.8%Value $36.39MPrice $20.22Shares 1.44MSince Jun 30 -20.08%
| Stock | Weight | Value | Since Jun 30 | Shares change | Action |
|---|---|---|---|---|---|
| 19.6% | $899.06M | -25.22% | — | Hold | |
| 13.3% | $613.03M | -29.74% | +6.76% | Add | |
| 10.0% | $457.55M | -22.43% | +1.22% | Add | |
| 8.0% | $367.19M | +4.62% | — | Hold | |
| 5.6% | $258.91M | +2.02% | — | Hold | |
| 4.0% | $185.37M | -22.68% | -0.00% | Trim | |
| 3.9% | $178.89M | -9.85% | — | Hold | |
| 3.3% | $150.18M | -9.45% | +10.20% | Add | |
| 2.9% | $135.26M | -32.17% | — | Hold | |
| 2.9% | $134.85M | -9.04% | — | Hold | |
| 2.5% | $115.31M | -11.43% | -55.10% | Trim | |
| 2.2% | $99.09M | -9.94% | — | Hold | |
| 2.2% | $98.81M | -22.95% | — | Hold | |
| 1.5% | $70.03M | -27.01% | — | Hold | |
| 1.3% | $60.05M | -7.68% | +68.87% | Add | |
| 1.3% | $59.88M | -17.53% | — | Hold | |
| 1.1% | $52.57M | +16.59% | — | New | |
| 1.1% | $50.41M | -13.38% | +39.22% | Add | |
| 1.1% | $49.72M | +17.76% | — | New | |
| 1.0% | $46.83M | -0.43% | — | Hold | |
| 1.0% | $46.69M | -22.12% | +491.22% | Add | |
| 1.0% | $45.86M | +21.85% | — | Hold | |
| 0.9% | $40.09M | -17.30% | — | Hold | |
| 0.8% | $36.71M | -22.13% | — | Hold | |
| 0.8% | $36.39M | -20.08% | — | Hold |
Weight is the share of the reported 13F value, including options at notional value. “Since Jun 30” compares the latest close with the quarter-end price implied by the filing (value ÷ shares).
Largest buys in 2026 Q2
Largest sells in 2026 Q2
Source: SEC Form 13F, values as reported by the filer. Filings lag up to 45 days after quarter end and cover only certain long positions. Research only, not investment advice.