Paradigm Biocapital Advisors LP
13F filer · CIK 1855655 · New York, NY
Summary
Paradigm Biocapital Advisors LP reported $5.34B across 28 positions in its 13F for 2026 Q2, filed Aug 14, 2026. The largest holdings are RVMD (22.3%), NUVL (13.7%), EWTX (7.8%). Versus 2026 Q1, leaving options aside, it opened 7 new positions, added to 12, trimmed 7 and sold out of 14.
Reported value$5.34B
Positions28
Report period2026 Q2
FiledAug 14, 2026
New positions7
Added12
Trimmed7
Sold out14
Top 25 holdings
By reported value, options listed separately · change vs 2026 Q1
Weight 22.3%Value $1.19BPrice $204.48Shares 6.36M -4.42%Since Jun 30 +9.18%
Weight 13.7%Value $731.67MPrice $123.96Shares 5.92M +11.27%Since Jun 30 +0.37%
Weight 7.8%Value $415.05MPrice $39.19Shares 10.22M +38.70%Since Jun 30 -3.54%
Weight 6.8%Value $360.77MPrice $35.57Shares 13.13M +64.83%Since Jun 30 +29.49%
Weight 6.4%Value $340.98MPrice $84.72Shares 3.84M +96.23%Since Jun 30 -4.57%
Weight 3.9%Value $209.23MPrice $135.07Shares 1.58M +16.92%Since Jun 30 +1.76%
Weight 3.8%Value $204.09MPrice $82.15Shares 2.14M -7.58%Since Jun 30 -13.68%
Weight 3.7%Value $198.74MPrice $24.42Shares 6.36M +58.55%Since Jun 30 -21.88%
Weight 3.6%Value $189.84MPrice $166.66Shares 1.23M +10.59%Since Jun 30 +8.23%
Weight 3.3%Value $174.96MPrice $14.21Shares 9.55M -8.11%Since Jun 30 -22.43%
Weight 3.3%Value $174.70MPrice $76.69Shares 2.78M +8.33%Since Jun 30 +21.85%
Weight 2.7%Value $144.49MPrice $254.07Shares 480KSince Jun 30 -15.60%
Weight 2.6%Value $141.38MPrice $115.63Shares 1.33M +5.70%Since Jun 30 +8.45%
Weight 2.6%Value $138.44MPrice $57.75Shares 2.51MSince Jun 30 +4.62%
Weight 2.3%Value $123.69MPrice $56.69Shares 2.13M -55.61%Since Jun 30 -2.48%
Weight 2.3%Value $123.52MPrice $20.00Shares 6.72M +113.53%Since Jun 30 +8.85%
Weight 2.0%Value $108.47MPrice $8.54Shares 8.67M +8.10%Since Jun 30 -31.73%
Weight 1.2%Value $63.49MPrice $14.18Shares 2.86MSince Jun 30 -36.18%
Weight 1.1%Value $58.41MPrice $21.98Shares 1.83M -11.02%Since Jun 30 -31.18%
Weight 0.8%Value $42.70MPrice $23.48Shares 1.55M +133.56%Since Jun 30 -14.56%
Weight 0.8%Value $41.33MPrice $3.42Shares 2.89M -8.02%Since Jun 30 -76.08%
Weight 0.6%Value $32.34MPrice $7.69Shares 4.95MSince Jun 30 +17.76%
Weight 0.6%Value $32.22MPrice $18.33Shares 1.75MSince Jun 30 -0.43%
Weight 0.5%Value $24.58MPrice $10.15Shares 686KSince Jun 30 -71.68%
Weight 0.4%Value $21.46MPrice $14.66Shares 900KSince Jun 30 -38.53%
| Stock | Weight | Value | Since Jun 30 | Shares change | Action |
|---|---|---|---|---|---|
| 22.3% | $1.19B | +9.18% | -4.42% | Trim | |
| 13.7% | $731.67M | +0.37% | +11.27% | Add | |
| 7.8% | $415.05M | -3.54% | +38.70% | Add | |
| 6.8% | $360.77M | +29.49% | +64.83% | Add | |
| 6.4% | $340.98M | -4.57% | +96.23% | Add | |
| 3.9% | $209.23M | +1.76% | +16.92% | Add | |
| 3.8% | $204.09M | -13.68% | -7.58% | Trim | |
| 3.7% | $198.74M | -21.88% | +58.55% | Add | |
| 3.6% | $189.84M | +8.23% | +10.59% | Add | |
| 3.3% | $174.96M | -22.43% | -8.11% | Trim | |
| 3.3% | $174.70M | +21.85% | +8.33% | Add | |
| 2.7% | $144.49M | -15.60% | — | New | |
| 2.6% | $141.38M | +8.45% | +5.70% | Add | |
| 2.6% | $138.44M | +4.62% | — | New | |
| 2.3% | $123.69M | -2.48% | -55.61% | Trim | |
| 2.3% | $123.52M | +8.85% | +113.53% | Add | |
| 2.0% | $108.47M | -31.73% | +8.10% | Add | |
| 1.2% | $63.49M | -36.18% | — | New | |
| 1.1% | $58.41M | -31.18% | -11.02% | Trim | |
| 0.8% | $42.70M | -14.56% | +133.56% | Add | |
| 0.8% | $41.33M | -76.08% | -8.02% | Trim | |
| 0.6% | $32.34M | +17.76% | — | New | |
| 0.6% | $32.22M | -0.43% | — | Hold | |
| 0.5% | $24.58M | -71.68% | — | New | |
| 0.4% | $21.46M | -38.53% | — | New |
Weight is the share of the reported 13F value, including options at notional value. “Since Jun 30” compares the latest close with the quarter-end price implied by the filing (value ÷ shares).
Largest buys in 2026 Q2
Largest sells in 2026 Q2
Source: SEC Form 13F, values as reported by the filer. Filings lag up to 45 days after quarter end and cover only certain long positions. Research only, not investment advice.