RTW INVESTMENTS, LP
13F filer · CIK 1493215 · New York, NY
Summary
RTW INVESTMENTS, LP reported $11.71B across 84 positions in its 13F for 2026 Q2, filed Aug 14, 2026. The largest holdings are MDGL (9.1%), ARGX (5.6%), PTCT (5.4%). Versus 2026 Q1, leaving options aside, it opened 9 new positions, added to 26, trimmed 8 and sold out of 13.
Reported value$11.71B
Positions84
Report period2026 Q2
FiledAug 14, 2026
New positions9
Added26
Trimmed8
Sold out13
Top 25 holdings
By reported value, options listed separately · change vs 2026 Q1
Weight 9.1%Value $1.07BPrice $509.44Shares 1.99MSince Jun 30 -5.12%
Weight 5.6%Value $658.20MPrice $970.66Shares 709KSince Jun 30 +4.62%
Weight 5.4%Value $631.88MPrice $64.96Shares 7.75MSince Jun 30 -20.36%
Weight 5.3%Value $620.40MPrice $140.97Shares 5.06M +0.04%Since Jun 30 +15.00%
Weight 5.2%Value $604.96MPrice $70.52Shares 8.51M +21.90%Since Jun 30 -0.75%
Weight 4.4%Value $516.35MPrice $115.63Shares 4.84MSince Jun 30 +8.45%
Weight 3.7%Value $434.53MPrice $24.42Shares 13.90M +4.51%Since Jun 30 -21.88%
Weight 3.2%Value $377.49MPrice $84.72Shares 4.25M +1.92%Since Jun 30 -4.57%
Weight 3.0%Value $345.76MPrice $77.38Shares 3.30M +8.73%Since Jun 30 -26.04%
Weight 2.8%Value $328.78MPrice $14.21Shares 17.95M +11.08%Since Jun 30 -22.43%
Weight 2.6%Value $298.91MPrice $70.65Shares 4.85M +13.11%Since Jun 30 +14.56%
Weight 2.6%Value $298.74MPrice $82.15Shares 3.14M +52.52%Since Jun 30 -13.68%
Weight 2.3%Value $271.45MPrice $414.52Shares 1.00M -20.00%Since Jun 30 +52.71%
Weight 2.2%Value $260.34MPrice $15.32Shares 7.80M +113.68%Since Jun 30 -54.12%
Weight 2.2%Value $259.62MPrice $114.22Shares 2.18M +30.81%Since Jun 30 -3.98%
Weight 2.1%Value $243.81MPrice $65.64Shares 2.86M +5.18%Since Jun 30 -22.95%
Weight 2.0%Value $237.41MPrice $10.99Shares 10.78MSince Jun 30 -50.11%
Weight 1.9%Value $227.89MPrice $63.70Shares 2.66MSince Jun 30 -25.77%
Weight 1.9%Value $222.20MPrice $177.73Shares 1.48MSince Jun 30 +18.46%
Weight 1.8%Value $213.69MPrice $138.35Shares 1.27M +19.38%Since Jun 30 -17.91%
Weight 1.8%Value $211.29MPrice $76.69Shares 3.36M +0.33%Since Jun 30 +21.85%
Weight 1.6%Value $184.00MPrice $25.88Shares 5.62MSince Jun 30 -20.90%
Weight 1.5%Value $181.55MPrice $24.51Shares 3.94M +52.40%Since Jun 30 -46.79%
Weight 1.5%Value $180.76MPrice $20.22Shares 7.14MSince Jun 30 -20.08%
Weight 1.4%Value $169.27MPrice $194.57Shares 1.24M +2.87%Since Jun 30 +42.60%
| Stock | Weight | Value | Since Jun 30 | Shares change | Action |
|---|---|---|---|---|---|
| 9.1% | $1.07B | -5.12% | — | Hold | |
| 5.6% | $658.20M | +4.62% | — | Hold | |
| 5.4% | $631.88M | -20.36% | — | Hold | |
| 5.3% | $620.40M | +15.00% | +0.04% | Add | |
| 5.2% | $604.96M | -0.75% | +21.90% | Add | |
| 4.4% | $516.35M | +8.45% | — | Hold | |
| 3.7% | $434.53M | -21.88% | +4.51% | Add | |
| 3.2% | $377.49M | -4.57% | +1.92% | Add | |
| 3.0% | $345.76M | -26.04% | +8.73% | Add | |
| 2.8% | $328.78M | -22.43% | +11.08% | Add | |
| 2.6% | $298.91M | +14.56% | +13.11% | Add | |
| 2.6% | $298.74M | -13.68% | +52.52% | Add | |
| 2.3% | $271.45M | +52.71% | -20.00% | Trim | |
| 2.2% | $260.34M | -54.12% | +113.68% | Add | |
| 2.2% | $259.62M | -3.98% | +30.81% | Add | |
| 2.1% | $243.81M | -22.95% | +5.18% | Add | |
| 2.0% | $237.41M | -50.11% | — | New | |
| 1.9% | $227.89M | -25.77% | — | Hold | |
| 1.9% | $222.20M | +18.46% | — | Hold | |
| 1.8% | $213.69M | -17.91% | +19.38% | Add | |
| 1.8% | $211.29M | +21.85% | +0.33% | Add | |
| 1.6% | $184.00M | -20.90% | — | Hold | |
| 1.5% | $181.55M | -46.79% | +52.40% | Add | |
| 1.5% | $180.76M | -20.08% | — | Hold | |
| 1.4% | $169.27M | +42.60% | +2.87% | Add |
Weight is the share of the reported 13F value, including options at notional value. “Since Jun 30” compares the latest close with the quarter-end price implied by the filing (value ÷ shares).
Largest buys in 2026 Q2
Largest sells in 2026 Q2
Source: SEC Form 13F, values as reported by the filer. Filings lag up to 45 days after quarter end and cover only certain long positions. Research only, not investment advice.