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PERCEPTIVE ADVISORS LLC

13F filer · CIK 1224962 · New York, NY

Summary
PERCEPTIVE ADVISORS LLC reported $6.66B across 109 positions in its 13F for 2026 Q2, filed Aug 14, 2026. The largest holdings are PRAX (10.2%), SYRE (5.8%), CELC (5.0%). Versus 2026 Q1, leaving options aside, it opened 23 new positions, added to 30, trimmed 26 and sold out of 13.
Reported value$6.66B
Positions109incl. options
Report period2026 Q2
FiledAug 14, 2026
New positions23
Added30
Trimmed26
Sold out13

Top 25 holdings

By reported value, options listed separately · change vs 2026 Q1

Weight 10.2%Value $681.63MPrice $281.00Shares 2.04MSince Jun 30 -16.07%
Weight 5.8%Value $383.48MPrice $84.72Shares 4.32M +14.17%Since Jun 30 -4.57%
Weight 5.0%Value $334.49MPrice $77.38Shares 3.20M +2.24%Since Jun 30 -26.04%
Weight 4.7%Value $310.39MPrice $228.07Shares 1.16MSince Jun 30 -14.49%
Weight 4.3%Value $287.16MPrice $95.71Shares 2.59M +8.95%Since Jun 30 -13.80%
Weight 4.3%Value $286.14MPrice $36.50Shares 8.09M -2.41%Since Jun 30 +3.14%
Weight 4.0%Value $263.93MPrice $18.36Shares 14.11M +44.66%Since Jun 30 -1.87%
Weight 3.2%Value $213.18MPrice $59.99Shares 3.75M -9.41%Since Jun 30 +5.60%
Weight 2.9%Value $195.59MPrice $14.66Shares 8.20MSince Jun 30 -38.53%
Weight 2.9%Value $195.19MPrice $123.96Shares 1.58MSince Jun 30 +0.37%
Weight 2.7%Value $177.71MPrice $39.19Shares 4.37M -1.13%Since Jun 30 -3.54%
Weight 2.6%Value $173.63MPrice $135.07Shares 1.31M -15.08%Since Jun 30 +1.76%
Weight 2.2%Value $149.69MPrice $29.28Shares 8.33M +0.60%Since Jun 30 +63.03%
Weight 2.2%Value $145.73MPrice $11.13Shares 10.79M +4.46%Since Jun 30 -17.62%
Weight 1.9%Value $128.01MPrice $82.15Shares 1.35M -3.61%Since Jun 30 -13.68%
Weight 1.8%Value $122.96MPrice $104.83Shares 1.30M -10.05%Since Jun 30 +10.64%
Weight 1.8%Value $120.36MPrice $140.97Shares 982K -20.23%Since Jun 30 +15.00%
Weight 1.8%Value $118.95MPrice $7.16Shares 11.91MSince Jun 30 -28.33%
Weight 1.6%Value $109.34MPrice $27.20Shares 4.18M +19.17%Since Jun 30 +4.06%
Weight 1.6%Value $105.57MPrice $24.42Shares 3.38M +317.87%Since Jun 30 -21.88%
Weight 1.6%Value $105.18MPrice $8.56Shares 10.38MSince Jun 30 -15.50%
Weight 1.6%Value $104.81MPrice $23.67Shares 4.32M +16.43%Since Jun 30 -2.41%
Weight 1.5%Value $103.09MPrice $8.27Shares 10.31M +38.67%Since Jun 30 -17.30%
Weight 1.5%Value $98.81MPrice $204.48Shares 528K +104.02%Since Jun 30 +9.18%
Weight 1.3%Value $88.07MPrice $27.10Shares 2.68MSince Jun 30 -17.68%

Weight is the share of the reported 13F value, including options at notional value. “Since Jun 30” compares the latest close with the quarter-end price implied by the filing (value ÷ shares).

Largest buys in 2026 Q2

Largest sells in 2026 Q2

Options

Notional value, listed apart from stocks

Source: SEC Form 13F, values as reported by the filer. Filings lag up to 45 days after quarter end and cover only certain long positions. Research only, not investment advice.

Original filing All 13F filings on EDGAR